Autonomous driving paper index
Metabolic reprogramming in cardiac fibrosis: mechanisms, crosstalk, and therapeutic interventions
One-line summary
Cardiac fibrosis is a pathological process accompanied by the development of cardiovascular diseases, which is mainly manifested as excessive deposition of extracellular matrix (ECM) of the heart muscle.
Engineering notes
Recent studies indicate that metabolic reprogramming significantly influences fibroblast activation, collagen deposition, and the fibrotic process by reshaping glycolytic, lipid, and amino acid metabolic pathways.
Chinese explanation / 中文解读
中文解读待补充：本站会优先为端到端自动驾驶、BEV感知、3D目标检测、轨迹预测、路径规划、LiDAR感知等高价值论文补充中文说明。
Original abstract
Cardiac fibrosis is a pathological process accompanied by the development of cardiovascular diseases, which is mainly manifested as excessive deposition of extracellular matrix (ECM) of the heart muscle. Recent studies indicate that metabolic reprogramming significantly influences fibroblast activation, collagen deposition, and the fibrotic process by reshaping glycolytic, lipid, and amino acid metabolic pathways. This paper systematically reviews the mechanism of metabolic reprogramming in cardiac fibrosis and puts forward potential intervention strategies from a critical perspective. Although metabolic reprogramming shows potential in regulating cardiac fibrosis, its practical application still faces major challenges. Future research should strive to build a comprehensive research framework and promote metabolic reprogramming research to open a new way of precise intervention for the prevention and treatment of cardiac fibrosis through cross−technological innovation and precise regulation.
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